Calprotect technology highlighted as one of the most important discoveries of 2019

The findings by the team of Dr. Alexandru Schiopu on the beneficial therapeutic effects of calprotectin blockade in myocardial infarction have been highlighted as one of the most important discoveries of 2019 in coronary artery disease. The study has been included in the yearly European Heart Journal editorial “The year in cardiology: acute coronary syndromes 2019”.

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The year in cardiology: acute coronary syndromes 2019

First proof-of-concept study showing that short-term blockade of calprotectin improves heart function after myocardial infarction

The research team of Dr. Alexandru Schiopu at Lund University published the first proof-of-concept study showing that short-term blockade of calprotectin (S100A8/A9) with a small molecule therapeutic inhibits inflammation, reduces heart damage and improves heart function in mice with myocardial infarction (MI). The study has been published in the European Heart Journal, the top-ranked international journal in the cardiovascular field.

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Inhibition of inflammation by short-term S100A9 blockade improves cardiac function after myocardial infarction